Fangyun 2005 Chinese Flare Mudan
166p. ISBN 7-5038-3968-6 book on Rockii-hybrid tree peonies in
chinese language, with many pictures
D Y & Castroviejo S, 2005:(1682)
Proposal to conserve the name Paeonia broteri against P.
lusitanica Mill. Taxon 54(1): 211-212.
to a local copy .pdf-file)
D Y & Pan K Y, 2005: Notes on
taxonomy of Paeonia Sect. Moutan DC. Acta
Phytotax. Sin. 43(2):169-177 (PDF:
to a local copy .pdf-file)
D Y & Pan K Y,
2005: Additional notes on taxonomy of
Paeonia sect. Moutan DC. Acta Phytotax.
Sin. 43(3):284-287 (PDF:
to a local copy .pdf-file)
paper deals with six combinations proposed in 2001 in Paeonia
sect. Moutan. Paeonia linyanshanii (S. G. Haw & Lauener) B. A.
Shen and P. linyanshanii ssp. taibaishanica (D. Y. Hong) B. A.
Shen are recognized as illegitimate names, P. ostii T. Hong &
J. X. Zhang ssp. lishizhenenii (lishizhenii) (B. A. Shen) B. A.
Shen is reduced to synonymy of P. ostii, P. delavayi Franch. ssp.
angustiloba (Rehder & E. H. Wilson) B. A. Shen and P. delavayi
ssp. lutea (Delavay ex Franch.) B. A. Shen are reduced to synonymy
of P. delavayi, and P. delavayi ssp. ludlowii (Stern & Taylor)
B. A. Shen is reduced to synonymy of P. ludlowii (Stern &
Taylor) D. Y. Hong.]
D Y : Paeonia
in the Mediterranean & Caucasus,
Presentation on the International Peony Symposium in Munich. May 7
Jiajue (Ed.) 2005, Zhongguo Mudan
PinZhong Tuzhi [Xibei, Xinan, Jiangnan] Jingwen ban, (Chinese
Tree Peony Cultivar Groups [Northwest, Southwest,
Yangtse] (English Edition) China Forestry Publishing House, 2005.
content of the book see here.
ZQ, Zhou H, Liu L, Jiang ZH, Wong YF, Xie Y, Cai X, Xu HX, Chan K.
Influence of co-administrated sinomenine on
pharmacokinetic fate of paeoniflorin in unrestrained conscious
rats. J Ethnopharmacol. 2005 May 13;99(1):61-7.
[Abstract: Paeonia lactiflora Pall.
(Ranunculaceae) root and Sinomenium acutum Rehder and Wilson
(Menispermaceae) stem are two herbs widely used in Chinese
medicine to treat rheumatoid arthritis. While, in theory, either
herb could be used alone, in practice, Chinese medicine
practitioners prescribe them together. Studies on pharmacokinetic
interaction between the active constituents of these two herbs
(paeoniflorin and sinomenine, respectively) provide empirical
evidence to support their clinical practice. A single dose of
paeoniflorin (150 mg/kg) alone and with sinomenine hydrochloride
(90 mg/kg) was administered by gastric gavage to unrestrained
conscious male Sprague-Dawley rats (n=6, 250-300 g). Blood samples
were collected periodically via a jugular vein before and after
dosing from 10 min to 12 h. A high-performance liquid
chromatographic (HPLC) assay was developed to determine the plasma
concentrations of paeoniflorin. Non-compartmental pharmacokinetic
profiles were constructed by using the software PK Solutions 2.0.
The pharmacokinetic parameters were compared using unpaired
Student t-test. After co-administration of sinomenine, the peak
plasma concentration of paeoniflorin was elevated (P<0.01), the
peak time was delayed (P<0.01), the AUC(0-t) was increased
(P<0.001), the mean residence time (MRT) was prolonged
(P<0.01), the C(L) was decreased (P<0.01) and the V(d) was
reduced (P<0.05). These results indicate that sinomenine
hydrochloride at 90 mg/kg significantly improved the
bioavailability of paeoniflorin in rats.] School of Chinese
Medicine, Hong Kong Baptist University, Kowloon Tong, Kowloon,
Hong Kong, PR China.
XJ, Chen SW, Wang WJ, Wang R, Zhang YJ, Li WJ, Li YL.,
Anxiolytic-like effect of paeonol in mice.,
Pharmacol Biochem Behav. 2005 Jun 19; [Department of
Pharmacology, Shenyang Pharmaceutical University, Box 41, 103
Wenhua Road, 110016 Shenyang, P.R. China.] [Abstract:
The present study in mice compared the putative anxiolytic-like
effect of paeonol, a phenolic component from the root bark of
Paeonia moutan, with the benzodiazepine diazepam in the elevated
plus maze and the light/dark box-test. The comparison was also
with regard to locomotor activity (open-field test) and
myorelaxant potential (inclined plane test). As with 2 mg/kg
diazepam, paeonol (at 17.5 mg/kg) increased the percentage of time
spent on open arms in the elevated plus maze and increased the
time spent in the light area of the light/dark box (at 8.75 and
17.5 mg/kg). Since paeonol, in contrast to diazepam, had no effect
on either the number of squares entered in the open-field test or
in the inclined plane test, its side-effect profile is considered
as superior to the benzodiazepine.] PMID: 15970315 [PubMed - as
supplied by publisher]
Martin, The gardener's peony: herbaceous and tree peonies,
2005, Timber Press 267p. ISBN 0-88192-694-9
S, Chung HS, Kang M, Lee E, Cho C, Kim H, Park S, Kim HY, Hong M,
Shin M, Bae H. Inhibition
of production of reactive oxygen species and gene expression
profile by treatment of ethanol extract of moutan cortex radicis
in oxidative stressed PC12 cells. Biol Pharm Bull.
2005 Apr;28(4):661-6. [Abstract: Moutan Cortex Radicis
(MCR) is one of the most widely used Oriental medicines. In this
study, we assessed the reducing effect of ethanol extract of MCR
on hydrogen peroxide-induced reactive oxygen production, the main
cause of cell damage or death in PC12 cells. The viability of
cells treated with 1 mg/ml of MCR was significantly restored from
that of oxidative-stressed PC12 cells. Measurement of
intracellular reactive oxygen species (ROS) generation was
determined using the H(2)DCFDA assay. MCR at 1-0.01 mg/ml
concentration inhibited ROS production in oxidative-stressed
cells. To identify candidate genes responsible for the
anti-oxidative effects of MCR on PC12 cells, an oligonucleotide
microarray analysis was performed. The result of gene expression
profiles showed that 10 genes were up-regulated and 7 were
down-regulated in MCR plus hydrogen peroxide treated cells
compared with hydrogen peroxide treated cells. Among them, heme
oxygenase (HO) and cathechol-O-methyltransferase (COMT) are
related to regulation of ROS generation and the others are known
to regulate cell survival and progression. Subsequently, we
performed real-time RT-PCR to quantify the ROS related gene. MCR
treatment increased the expression of HO by 370% and COMT by 280%
at the concentration of 1 mg/ml. These findings suggest that MCR
inhibits the production of ROS and cytotoxicity by
oxidative-stressed PC12 cells through over-expression of HO and
COMT.] College of Oriental Medicine, Kyung-Hee University, Seoul,
Republic of Korea, Click here
ZHANG HuiJin, ZHANG ZhiMing, CHEN FuFei, CHEN FuHui: DNA
molecular evidences of the hybrids between P. rockii and P.
suffruticosa based on ISSR markers. Acta Botanica Yunnanica
2005. 27(1): 42 8.
rockii is considered to be one of the main progenitors of Chinese
tree peony cultivars, and hybridization is likely to be the most
important way for incorporation of genetic composition of P.
rockii. However, no molecular evidence has shown relatedness of
woody peony cultivars to P. rockii so far. In this study, P.
rockii was used as a maternal parent crossing with other three
Chinese woody peony cultivars (P. suffruticosa Hai Tang
Zheng Rong, P. suffruticosa Yan Zhi Hong and P.
suffruticosa Sheng Dan Lu) as paternal parents.The
relationships between the F1 hybrids and their parents were
analyzed using ISSR (Inter-simple sequence repeat) markers. Our
results showed that ISSR fragments present in both parents were
detected in the genomes of the F1 generation. Therefore, it is
possible that some Chinese woody peony cultivars with a large
black-purple blotch at the lower part of petals originated through
hybridization with P. rockii as a parent. Our results also suggest
that ISSR markers are useful for identification of hybrids and
classification of cultivars.]
H, Wei W, Wang NP, Wu CY, Yan SX, Yue L, Zhang LL, Xu SY.
Effects of total glucosides of peony on
immunological hepatic fibrosis in rats. World J
Gastroenterol. 2005 Apr 14;11(14):2124-9. [Abstract:
To study the effects of total glucosides of peony (TGP) on
immunological hepatic fibrosis induced by human albumin in rats.
METHODS: Sixty adult male Sprague-Dawley rats were randomly
divided into: Normal group, model group, TGP (60 and 120 mg/kg)
treatment groups and colchicines (0.1 mg/kg) treatment group. On
the day before the rats were killed, those in TGP or colchicine
groups received TGP or colchicine as above from the first day of
tail vein injection of human albumin. The rats in normal and model
groups were only administered with the same volume of vehicle. At
the end of the 16th wk, rats in each group were killed. Blood and
tissue specimens were taken. Levels of alanine aminotransferase
(ALT), aspartate aminotransferase (AST), nitric oxide (NO),
content of malondialdehyde (MDA), activity of superoxide dismutase
(SOD) and glutathione peroxidase (GSH-px), were measured by
biochemical methods. Serum procollagen type III (PC III) and
laminin (LN) were determined by radioimmunoassay. Liver collagen
level was determined by measuring hydroxyproline content in fresh
liver samples. Hepatic tissue sections were stained with
hematoxylin-eosin and examined under a light microscope. RESULTS:
Histological results showed that TGP improved the human
albumin-induced alterations in the liver structure, alleviated
lobular necrosis and significantly lowered collagen content. The
antifibrotic effect of TGP was also confirmed by decreased serum
content of LN and PCIII in TGP-treated group. Moreover, the
treatment with TGP effectively reduced the hydroxyproline content
in liver homogenates. However, the level of ALT and AST increased
in fibrotic rat but had no significance compared with normal
control, whereas the ratio of A/G decreased without significance.
TGP had no effect on level of ALT, AST and the ratio of A/G.
Furthermore, TGP treatment significantly blocked the increase in
MDA and NO, associated with a partial elevation in liver total
antioxidant capacity including SOD and GSH-px. CONCLUSION: TGP has
beneficial effects on hepatic fibrosis in rats by inhibition of
collagen synthesis and decreasing oxidative stress.]
Institute of Clinical Pharmacology, Anhui Medical University,
Hefei 230032, Anhui Province, China. Click here
to read full conplete article.
Jianguo & Zhang Zuoshuang. Herbaceous Peonies of China,
ISBN 7 5038 3961 9.
X, Cheng C, Sun Q, Li F, Liu J, Zheng C.
Isolation and purification of four flavonoid
constituents from the flowers of Paeonia suffruticosa by
high-speed counter-current chromatography. J Chromatogr
A. 2005 May 20;1075(1-2):127-31. [Abstract:
Four flavonoids, apigenin-7-O-neohesperidoside,
luteolin-7-O-glucoside, apigenin-7-O-glucoside and
kaempferol-7-O-glucoside have been isolated and purified for the
first time from the flowers of Paeonia suffruticosa by high-speed
counter-current chromatography with a two-phase solvent system
composed of ethyl acetate-ethanol-acetic acid-water (4:1:0.25:5,
v/v). Then, 5 mg apigenin-7-O-neohesperidoside, 4 mg
luteolin-7-O-glucoside, 9 mg apigenin-7-O-glucoside and 2.5 mg
kaempferol-7-O-glucoside could be obtained after injecting 40 mg
sample and their purities were 94, 97, 97 and 96%, respectively.
All these constituents were identified by mass spectrometry and
nuclear magnetic resonance.] Test Center, Shandong Academy
of Sciences, 19 Keyuan Street, Jinan, Shandong 250014, China.
Xiangyun1; Hong, Tao2
(2005): Validation and neotypification of
Paeonia rockii subsp. linyanshanii (Paeoniaceae). Taxon,
Volume 54, Number 3, August 2005, pp. 806-807(2), Publisher:
International Association for Plant Taxonomy [Abstract:
"Paeonia rockii subsp. linyanshanii T. Hong & G. L. Osti"
was not validly published in 1994 because it was assigned to
"Paeonia rockii (S. G. Haw & L. A. Lauener) T. Hong &
J. J. Li", which was not then a validly published name.
Although the species name was validated in 1998 as Paeonia rockii
(S. G. Haw & L. A. Lauener) T. Hong & J. J. Li ex D. Y.
Hong, P. rockii subsp. linyanshanii has still not been validly
published, although P. suffruticosa var. linyanshanii J. J. Halda
was validly published in 1997. P. rockii subsp. linyanshanii is
validated here, based on Handa's varietal name, and, because the
holotype was not preserved, a neo-type is designated. Keywords:
PAEONIACEAE; PAEONIA ROCKII SUBSP. LINYANSHANII; VALIDATION
Affiliations: 1: Institute of Botany, the Chinese Academy of
Sciences, Beijing 100093, China 2: Chinese Academy of Forestry,
Beijing 100091, China] online available under the